Description

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Presenting state-of-the-art knowledge on diabetes research in animal models, this reference contains 22 reviews contributed by biochemists, physiologists, and cellular and molecular biologists from around the world. The editors include articles integrating cellular, molecular, and whole-body mechanisms related to insulin resistance in skeletal muscle. The book provides clinical insights on topics such as environmental and genetic factors leading to insulin resistance; basic elements of the signal transduction pathways leading to regulation of metabolic responses controlling glucose homeostasis; and transgenic approaches for the study of glucose metabolism in skeletal muscle.