Modelling the Short Qt Syndrome Gene Mutations: And Their Role in Cardiac Arrhythmogenesis (Springer Theses) (Paperback)
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Description
Ion Channels and the Action Potential.- Potassium Channels Implicated in the Short QT Syndrome.- The Short QT Syndrome.- Model Development.- Methods, Experimental Protocols and Mathematical Preliminaries.- Increased Vulnerability of the Human Ventricle to Re-entrant Excitation in hERG-linked SQT1.- Mathematically Modelling the Functional Consequences of the SQT2 Mutation.- Proarrhythmia in KCNJ2-linked Short QT Syndrome: Insights from Modelling.- Relationship between Electrical and Mechanical Systole in the Short QT Syndrome: Insights from Modelling.- Discussion and Conclusion.
